Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 10 - Jul 15
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
CD8 alpha&beta Heterodimer His Tag Protein, HumanProduct Specification Species Human Synonyms CD8A&CD8B; CD8 alpha&beta Accession P01732 1P10966 1 Amino Acid Sequence Ser22 Asp182&Leu22 Pro170, with 6His tag at the C terminus Expression System HEK293 Molecular Weight 30 40 kDa, reducing conditions Purity 95% by SDS PAGE Endotoxin <1EU g Conjugation Unconjugated Tag His Tag Physical Appearance Lyophilized Powder Storage Buffer PBS, 5% Trehalose, pH7. 4. Reconstitution Always centrifuge tubes before
Product Specification
| Species | Human |
| Synonyms | CD8A&CD8B; CD8 alpha&beta |
| Accession | P01732-1、P10966-1 |
| Amino Acid Sequence |
Ser22-Asp182&Leu22-Pro170, with 6His tag at the C-terminus
|
| Expression System | HEK293 |
| Molecular Weight |
30-40 kDa, reducing conditions
|
| Purity | ＞95% by SDS-PAGE |
| Endotoxin | <1EU/μg |
| Conjugation | Unconjugated |
| Tag | His Tag |
| Physical Appearance | Lyophilized Powder |
| Storage Buffer |
PBS, 5% Trehalose, pH7.4.
|
| Reconstitution |
|
| Stability & Storage |
Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. |
Background
CD8 is a heterodimeric membrane glycoprotein on MHC class I-restricted T lymphocytes that cooperates with the alpha beta CD3 TCR in the recognition of MHC class I molecules presenting antigenic peptides. Cell surface CD8 molecules exist as either alpha/alpha homodimers or alpha/beta heterodimers, and most CD8+ T cells that undergo differentiation in the thymus express alpha/beta heterodimers. The CD8 b chain appears to be important for the thymic maturation of CD8+ T cells, because the number of mature CD8 single-positive T cells is decreased in CD8b gene-disrupted mice and most CD8+ T cells among gut intraepithelial lymphocytes in thymectomized mice express CD8 alpha/alpha homodimers.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy