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The Memory Thief : And the Secrets Behind How We Remember: A Medical Mystery336 pages Hardcover The remarkable true story of a team of doctors who through years of scientific sleuthing and observant carediscover a surprising connection between opioids and memory, one that holds promise and peril for any one of us. How could you lose your memory overnight, and what would it mean? The day neurologist Jed Barash sees the baffling brain scan of a young patient with devastating amnesia marks the beginning of a quest to answer
336 pages | Hardcover
The remarkable true story of a team of doctors who – through years of scientific sleuthing and observant care—discover a surprising connection between opioids and memory, one that holds promise and peril for any one of us.
How could you lose your memory overnight, and what would it mean? The day neurologist Jed Barash sees the baffling brain scan of a young patient with devastating amnesia marks the beginning of a quest to answer those questions. First detected in a cluster of stigmatized opioid overdose victims in Massachusetts with severe damage to the hippocampus—the brain’s memory center—this rare syndrome reveals how the tragic plight of the unfortunate few can open the door to advances in medical science.
After overcoming initial skepticism that investigating the syndrome is worth the effort—and that fentanyl is the likely culprit—Barash and a growing team of dedicated doctors explore the threat that people who take opioids chronically as prescribed to treat severe pain may gradually put their memories at risk. At the same time, they begin to grasp the potential for this syndrome to shed light on the most elusive memory thief of all—Alzheimer’s disease.
Through the prism of this fascinating story, Aguirre goes on to examine how researchers tease out the fundamental nature of memory and the many mysteries still to be solved. Where do memories live? Why do we forget most of what happens in a day but remember some events with stunning clarity years later? How real are our memories? And what purpose do they actually serve?
Perhaps the greatest mystery in The Memory Thief is why Alzheimer’s has evaded capture for a century even though it afflicts tens of millions around the world and lies in wait for millions more. Aguirre deftly explores this question and reveals promising new strategies and developments that may finally break the long stalemate in the fight against this dreaded disease.
But at its core, Aguirre’s genre-bending and deeply-reported book is about paying attention to the things that initially don’t make sense—like the amnestic syndrome—and how these mysteries can move science closer to an ever-evolving version of the truth.
How could you lose your memory overnight, and what would it mean? The day neurologist Jed Barash sees the baffling brain scan of a young patient with devastating amnesia marks the beginning of a quest to answer those questions. First detected in a cluster of stigmatized opioid overdose victims in Massachusetts with severe damage to the hippocampus—the brain’s memory center—this rare syndrome reveals how the tragic plight of the unfortunate few can open the door to advances in medical science.
After overcoming initial skepticism that investigating the syndrome is worth the effort—and that fentanyl is the likely culprit—Barash and a growing team of dedicated doctors explore the threat that people who take opioids chronically as prescribed to treat severe pain may gradually put their memories at risk. At the same time, they begin to grasp the potential for this syndrome to shed light on the most elusive memory thief of all—Alzheimer’s disease.
Through the prism of this fascinating story, Aguirre goes on to examine how researchers tease out the fundamental nature of memory and the many mysteries still to be solved. Where do memories live? Why do we forget most of what happens in a day but remember some events with stunning clarity years later? How real are our memories? And what purpose do they actually serve?
Perhaps the greatest mystery in The Memory Thief is why Alzheimer’s has evaded capture for a century even though it afflicts tens of millions around the world and lies in wait for millions more. Aguirre deftly explores this question and reveals promising new strategies and developments that may finally break the long stalemate in the fight against this dreaded disease.
But at its core, Aguirre’s genre-bending and deeply-reported book is about paying attention to the things that initially don’t make sense—like the amnestic syndrome—and how these mysteries can move science closer to an ever-evolving version of the truth.
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4.5 ★★★★★
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Product Reviews
★★★★★ 5
Nice Fit
Color: Black, White, Light Gray, Size: 3X-Large
I picked this up looking for something simple but clean, and it delivered. The fit is comfortable, the material feels solid, and it looks good without needing much effort. It’s one of those pieces you can throw on and still look put together.
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Reviewed in the United States on March 29, 2026
★★★★★ 4
Good value, soft and comfortable
Color: Black, Army Green, Light Gray, Size: 4X-Large, Color: Black, Army Green, Light Gray, Size: 4X-Large
Initial thoughts are very positive with this 3 pack shirt set. The green is similar to an OD military green and the black and gray are standard color shades. Material is soft and sizes are true to size. The mock turtleneck isn’t too tight but may still be a little annoying to some people. I do question the amount of spandex in these shirts. Tag says 5% but these shirts are extremely stretchy and feels like a higher spandex content. It’s also a little tough to figure out which way is the front of the shirt. Visually rhe front does have a lower collar line than the back but would still be nice to have a brand tag printed in the back of the shirt for quicker identification.
Overall for roughly $12 a shirt these are a good choice for everyday wear. I will update rating if these shirts fail to meet expectations after further use.
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Reviewed in the United States on April 8, 2025
★★★★★ 5
👍🏻
Color: Black, Army Green, Light Gray, Size: 5X-Large
Weirdly thick material, I wasn’t a fan but it’s a good sleep shirt
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Reviewed in the United States on May 28, 2026
★★★★★ 5
Just what I wanted.
Color: Black, Navy Blue, Wine Red, Size: 5X-Large
These may have just become my standard shirt to wear. Feels good whether tucked or out. Drapes well and fits well. So far, I can see it adjust to the different undershirt I may wear. Will probably order another set in other colors and a back up set of the basics because they will get worn a lot.
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Reviewed in the United States on July 17, 2025
★★★★★ 3
Its alright
Color: Black, Size: 5X-Large
True to size per the size chart. The fabric is soft but it it feels cheap to me. It attracts lint but you can brush it off easily so its not the cheapest material I've dealt with. Also, it is opaque (not see through).
There is no front/ back indicator either which is indicative of a cheap shirt in my opinion. Would be friendly for tag sensitive people (to stay positive).
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Reviewed in the United States on April 14, 2026