Shipping Estimate
USA
- USA
- CAN
- USA
- CAN
Ships within 48 hours · Estimated delivery Jul 9 - Jul 14
Promo Codes Available:
For Your Every Summer RSVP, with Code: SUMMER15
Description
S-RMab® Cadherin 17 Recombinant Rabbit mAb,PBS Only (SDT-736-23)Product Specification Host Rabbit Antigen Cadherin 17 Synonyms LI cadherin, Intestinal peptide associated transporter HPT 1, Liver intestine cadherin, CDH17 Immunogen Synthetic Peptide Location Cell membrane Accession Q12864 Clone Number SDT 736 23 Antibody Type Recombinant mAb Isotype IgG Application WB, IHC P Reactivity Hu, Ms, Rt Purification Protein A Concentration 1 mg ml Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS
Product Specification
| Host | Rabbit |
| Antigen | Cadherin 17 |
| Synonyms | LI cadherin, Intestinal peptide-associated transporter HPT-1, Liver-intestine cadherin, CDH17 |
| Immunogen | Synthetic Peptide |
| Location | Cell membrane |
| Accession | Q12864 |
| Clone Number | SDT-736-23 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | WB, IHC-P |
| Reactivity | Hu, Ms, Rt |
| Purification | Protein A |
| Concentration | 1 mg/ml |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS |
| Stability & Storage | 12 months from date of receipt / reconstitution, 4 °C as supplied |
Dilution
| application | dilution | species |
| WB | 1:1000 | |
| IHC-P | 1:500-1:2000 |
Background
This gene is a member of the cadherin superfamily, genes encoding calcium-dependent, membrane-associated glycoproteins. The encoded protein is cadherin-like, consisting of an extracellular region, containing 7 cadherin domains, and a transmembrane region but lacking the conserved cytoplasmic domain. The protein is a component of the gastrointestinal tract and pancreatic ducts, acting as an intestinal proton-dependent peptide transporter in the first step in oral absorption of many medically important peptide-based drugs. The protein may also play a role in the morphological organization of liver and intestine. In normal tissues, LI cadherin antibodies are labeled on epithelial cells of the gastrointestinal and pancreatic tracts, but not on epithelial cells of the kidneys, liver, and other tissues. In tumors, it is expressed in digestive system adenocarcinoma, including cancer. It is a sensitive biomarker for distinguishing gastrointestinal metaplasia from well differentiated adenocarcinoma.
Shipping Notes
- Free Standard Shipping on $100+ Orders to the USA.
- Except Preorder products are shipped in 48 hours.
- Delivery to the USA:
- Standard Shipping : 3-10 business days
- If time is of the essence, please consider selecting expedited delivery for faster service.
Exchange/Return Notes
- We offer a 30-day return/exchange service after receiving.
- Final sale items are not eligible for returns or exchanges.
- To process your return/exchange, please contact us at [email protected]
- Please click here for more details>>> Return & Exchange Policy