SKU: 74327397550

PDGFRAlpha (5D1) Mouse mAb

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Description

PDGFRAlpha (5D1) Mouse mAbPlatelet derived growth factor (PDGF) family proteins exist as several disulphide bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor Alpha (PDGFRAlpha) and PDGF receptor Beta (PDGFRBeta). PDGFRAlpha and PDGFRBeta can each form heterodimers with EGFR, which is also activated by PDGF. Various cells differ in the total number of

Platelet derived growth factor (PDGF) family proteins exist as several disulphide-bonded, dimeric isoforms (PDGF AA, PDGF AB, PDGF BB, PDGF CC, and PDGF DD) that bind in a specific pattern to two closely related receptor tyrosine kinases, PDGF receptor Alpha (PDGFRAlpha) and PDGF receptor Beta (PDGFRBeta). PDGFRAlpha and PDGFRBeta can each form heterodimers with EGFR, which is also activated by PDGF. Various cells differ in the total number of receptors present and in the receptor subunit composition, which may account for responsive differences among cell types to PDGF binding. Ligand binding induces receptor dimerization and autophosphorylation, followed by binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules, such as GRB2, Src, GAP, PI3 kinase, PLCGamma, and NCK. A number of different signaling pathways are initiated by activated PDGF receptors and lead to control of cell growth, actin reorganization, migration, and differentiation.

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SKU: 74327397550

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Kara Williams
Alexandria, US
★★★★★ 5
Awesome
Super easy to use, fits plenty of stuff, and keeps everything in one place! Highly recommend if your “mom car” has a truck bed!
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Reviewed in the United States on May 13, 2026
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danette k hardesty
Houston, US
★★★★★ 5
Cargo net
Perfect fir your hauling needs
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Reviewed in the United States on May 18, 2026
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ShaZ
Carnegie, US
★★★★★ 3
Not gonna last!
It only arrived with 2 self-locking hooks which were made of plastic. Plastic will never hold up! Needless to say, it's being returned.
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Reviewed in the United States on May 21, 2025
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Yesiralmy
Houston, US
★★★★★ 5
truck bed net
It fits perfectly, just what I expected, good quality and it does the job
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Reviewed in the United States on February 9, 2026
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Eric
Cuba, US
★★★★★ 5
MVP of our Camping Trip
This net is unreal. We went camping and absolutely over filled our truck bed and this held everyone in. We had camping chairs, back packs. Fishing reels and paper towels. All kinds of loose stuff and it all stayed perfectly in place. I have been pleasantly surprised and would recommend this for anyone who wants a little security when they have anything in the bed! This totally have me peace of mind on our trip. I expected it to rip the way I was abusing it but nothing! It's still perfect. The hooks are well made and the netting is super strong. It stretches easily but holds stuff down tight. It's truly awesome.
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Reviewed in the United States on August 22, 2025

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