SKU: 80450254112

Protopic

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Description

ProtopicProtopic Description Protopic is a cream used on the skin to treat inflammation, such as perioral dermatitis. It blocks calcineurin, a protein that triggers your body's inflammatory cells, helping to reduce inflammation. Apply it twice daily until the affected area improves, then switch to twice a week to maintain your condition. Essential Information What is Protopic? Protopic ointment includes tacrolimus, which helps to lessen inflammation and

Protopic Description
Protopic is a cream used on the skin to treat inflammation, such as perioral dermatitis.
It blocks calcineurin, a protein that triggers your body's inflammatory cells, helping to reduce inflammation.
Apply it twice daily until the affected area improves, then switch to twice a week to maintain your condition.

What is Protopic?

Protopic ointment includes tacrolimus, which helps to lessen inflammation and itching. It's used to treat different types of dermatitis (skin irritation) when the condition is believed to be caused by an immune response.

Perioral dermatitis appears as a red rash around the mouth, often accompanied by itchiness and spots. The exact cause isn't completely known, but some believe that inflammation of the hair follicles might lead to spots forming around the mouth. Although topical steroids are commonly used to treat this condition, overuse can cause dermatitis when you stop using them. Other possible causes include hormonal changes, taking oral contraceptives, and fungal infections.

How does Protopic work?

Protopic contains tacrolimus, which is an immunomodulating agent that influences your immune system. When you apply it to your skin, it blocks calcineurin, which helps reduce inflammatory substances like mast cells, cytokines IL-2, and TNF-alpha. Consequently,

How is Protopic different from other treatments for perioral dermatitis?

Protopic is a type of immunosuppressant. It works by dampening the immune response, which helps to lessen inflammation and itching. Elidel is a similar medication to Protopic. It contains pimecrolimus, which also helps to reduce inflammation and is used to treat dermatitis.

If the affected area is severely infected, your doctor might prescribe antibiotics such as Lymecycline for a few weeks. This helps stop the bacteria causing the infection, which can ease itching and also reduce inflammation and spots.

How well does Protopic work for perioral dermatitis?

Tacrolimus has been shown to effectively treat dermatitis. A study from 2000 revealed that patients using 0.1% tacrolimus twice a day experienced noticeable improvements within a week (54%), with even better results after 6 months (81%) and a year (86%).

Moreover, when comparing tacrolimus to topical corticosteroids for treating atopic dermatitis, 71.6% of patients using tacrolimus showed more improvement within 3 months, compared to 50.8% of those using a steroid.

Important Information

Protopic isn't right for everyone, and there are a few things you should know when using it.

Here's all the official information on it. If anything isn't clear, just let our clinician know, and they can discuss it with you.

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SKU: 80450254112

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Haley Angilella
Whiting, US
★★★★★ 4
Very stylish but not the best quality
Color: Silvery Gold green dial, Color: Silvery Gold green dial
You are getting what you pay for: the color of the dial is amazing. It looks so stylish and can really accessorize an outfit. The packaging of the watch was very nice and it came with tools to adjust the size of the watch. However the links color is not the best color and quality. The watch feels light but in a cheaper feel. I’ve ordered other watches from Amazon that in my opinion were nicer and felt and looked high end. I got this watch on sale for Black Friday but I’m not sure if I would pay full price for it.
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Reviewed in the United States on January 14, 2026
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Herbert M.
Massapequa, US
★★★★★ 5
Bracelet opens too easy for any time activity
Color: Silvery green dial 5885
Watch face too small more for women tastes
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Reviewed in the United States on June 6, 2026
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Mike Smith
Natrona Heights, US
★★★★★ 1
Cheap watch
Color: 5885 steel black dial
Beautiful watch but don't get it wet....can't take a shower with it. Do not waste your money save up and get a good watch.
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Reviewed in the United States on May 20, 2026
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R. Nicholas Martin
Carnegie, US
★★★★★ 5
Best watch for the retail price!
Color: 5885 blue dial
Ease of use: All you have to do is put it on and it's self-winding and you never ever need to worry about batteries or winding it up! It's pretty accurate time as well and looks good! It's the best watch I've ever owned for this price and I even bought my son one for himself!
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Reviewed in the United States on July 4, 2025
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Reese Wright
Massapequa, US
★★★★★ 5
Real stainless band
Color: rose steel black dial, Color: rose steel black dial
My new favorite work watch. Wound up buying this after two failed attempts with other cheap watches from Wally world that turned my wrist black after the plating wore off in about three days. Learned my lesson. so far this thing keeps perfect time and does not turn my wrist black. Had to take a couple of links out for a perfect fit. So yeah, this will be the only brand of watch I will likely be buying from now on. Hope they’re around for a while. Update* January 8 2026. Oh no, I had such high hopes for this watch brand BUT, I only had this watch for two months when it started dry moisture inside the crystal. No I am not a diver nor have I had the watch fully submerged. This thing is not water resistant at all. It may be great for Desert dwellers or for people who never take showers or baths with it on. Going back to my old favorite Armitron.
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Reviewed in the United States on October 28, 2025

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